Migraine Treatment Optimization Questionnaire-4 (mTOQ-4)
Measures effectiveness of current migraine treatment plan.
Jennifer Glen
Provided byInadequate acute episodic migraine (EM) treatment efficacy has been associated with an increased risk of new-onset chronic migraine (CM) over the course of 1 year (Lipton et al., 2015). It is suggested that improving acute treatment outcomes might prevent new-onset CM. The Migraine Treatment Optimization Questionnaire (mTOQ-4) is a validated 4-item questionnaire that assesses acute treatment efficacy. The original validation work was conducted on the 19-item mTOQ but subsequent derivations have been studied, such as the mTOQ-4. Items in the mTOQ-4 have been shown to have test-retest reliability and validity, but the TOQ-4 has not been validated as a stand-alone measure.
.Summary
The Migraine Treatment Optimization Questionnaire (mTOQ-4) is a validated 4-item questionnaire that assesses acute treatment efficacy.
Scoring & Recommendations
The 4 questions will answer with one of the following:
| Answer | Points |
| Never or rarely | 0 |
| Less tan half the time | 1 |
| Half the time or greater | 2 |
The mTOQ-4 score is calculated by the addition of the selected points in each of the 4 questions and the following results display:
| mTOQ-4 Score | Treatment Effectiveness |
| 0 | Very poor treatment efficacy |
| 1-5 | Poor treatment efficacy |
| 6-7 | Moderate treatment efficacy |
| 8 | Maximum treatment efficacy |
Management
Higher scores correlate to better treatment efficacy and symptom control. Consider modifying therapy if scores are low.
.All questions & possible results
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After taking your migraine medication, are you pain-free within 2 hours for most attacks?
Select one option:
- Never or rarely
- Less than half the time
- Half the time or greater
Does 1 dose of your migraine medication usually relieve your headache and keep it away for at least 24 hours?
Select one option:
- Never or rarely
- Less than half the time
- Half the time or greater
Are you comfortable enough with your migraine medication to be able to plan your daily activities?
Select one option:
- Never or rarely
- Less than half the time
- Half the time or greater
After taking your migraine medication, do you feel in control of your migraines enough so that you feel you can return to normal function?
Select one option:
- Never or rarely
- Less than half the time
- Half the time or greater
Possible results
Literature
- Validity and reliability of the Migraine-Treatment Optimization Questionnaire. Cephalalgia. 2009 Jul;29(7):751-9. — Lipton RB, Kolodner K, Bigal ME, Valade D, Láinez MJ, Pascual J, Gendolla A, Bussone G, Islam N, Albert K, Parsons B.
- Ineffective acute treatment of episodic migraine is associated with new-onset chronic migraine. Neurology. 2015 Feb 17;84(7):688-95. — Lipton RB, Fanning KM, Serrano D, Reed ML, Cady R, Buse DC.